Influenza D has, historically, mainly affected farm animals like cattle and pigs, but there is evidence that it is now spreading through the human population. It has been found among farm workers, in hospitals, and even in airports. It spreads stealthily and quickly, barely triggering immune alarms. Infectious disease scientists are concerned that it might mark the start of the next global pandemic, and some are calling it "a legitimate pandemic threat requiring immediate surveillance".
Researchers have found that Influenza D replicates in human lungs just as efficiently as seasonal flu, but it had learnt to suppress the cellular alarm systems that normally alert the immune system to viral infection, allowing it to take hold and start replicating before normal defences can kick in.
Thing is, though, unlike the usual symptoms of seasonal flu - fever, aches, cough, runny nose - Influenza D has very mild or even no symptoms at all. So, people can go about their normal business while potentially spreading the virus to others unknowingly - ideal pandemic conditions.
But, if it usually has few or no symptoms why should we even worry about it? Well, scientists worry that it could learn to exchange genetic material with other viruses, allowing it to mutate into something more concerning for humans, and it could evade immune responses and antiviral interventions.
Well, maybe. But this is still very much in the realm of "what if". It may spread widely with little or no injurious symptoms. Or it may mutate, a little or a lot. Or an entirely different virus may appear on the scene with much greater pandemic potential. It's good that scientists are monitoring these things, but to call Influenza D the next big pandemic threat is probably a stretch.
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