Don't skimp.on your medications

A friend whose judgement I trust implicitly was talking recently about her niece who is a doctor in the UK. My friend also trusts her niece's judgement implicitly, so therefore so do I.

Anyway, the point is, this doctor had been kvetching about people who misuse everyday drugs (think, acetaminophen, iboprofin) by not taking as much as they were allowed, according to the label. They may be worried about overdosing, or concerned about developing a tolerance, a dependence, an addiction, that kind of thing.

Well, my wife is that kind of cautious drug-user. So, given that she is now having to rely on extra-strength Tylenol (acetaminophen) to mask some pretty severe back pain, at least until her appointment with a pain management clinic comes through, I decided to check on the dosage rules and recommendations.

According to Harvard Health Publishing, which I'm also inclined to trust, one should "be cautious but not afraid" of Tylenol, and trust the dosage information on the label. Yes, people occasionally suffer liver damage and some even (very occasionally) die from overdoses, but you'd have to work very hard at it. 

Some small portion of the drug is converted in the body to a by-product that is toxic to the liver, but you'd have to take an awful lot to build up more than the body can handle. Also, unlike NSAIDS (ibuprofen/Advil and naproxen/Aleve), high doses of acetaminophen will not irritate the stomach and intestinal lining. As for President Trump and Robert F. Kennedy's conspiracy theories about Tylenol, treat them with the contempt they deserve.

The maximum recommended daily dose of acetaminophen is 4,000 milligrams (mg) from all sources, although 3,000 mg is recommended, to be on the safe side. 

So, if you are taking regular (325 mg) tablets, no more than 8 to 10 a day are recommended. The label suggests 1 or 2 tablets every 4 to 6 hours, which is about at the top end of the recommended daily dosage (although few people would continue taking them every 4 hours overnight, I think).

Extra-strength tablets are 500 mg, and no more than 6 a day are recommended. The label suggests 1 or 2 tablets every 6 to 8 hours. Some extra-strength tablets (e.g. for arthritis) are 650 mg, and no more than 4 a day are recommended. The label says take 1 every 8 hours (i.e. 3 a day).

So, as can be seen, the recommended dosages are quite conservative, and you'd have to be flouting them pretty cavalierly to run any risk at all of liver damage. So, don't skimp, take the recommended doses. You'll feel better and you're very, very unlikely to do any damage to your internal organs.

UCP's plan to gerrymander Alberta's electoral districts

Michelle Smith's United Conservative Party (UCP) continues unabashedly down the path blazed by Donald Trump's Republicans. This time they are pursuing what seems to be a textbook case of gerrymandering - manipulating electoral district boundaries for partisan advantage.

Electoral districts DO need to be changed from time to time as population numbers and densities change. In Alberta, as in other provinces, an independent committee exists to do just that. But when a majority of that committee announced that their analysis called for an increase to the number of seats in Calgary and Edmonton to account for increased populations in thise cities, the UCP objected. 

You see, the cities of Calgary and Edmonton are strongholds of the opposition NDP party, and increasing seats there would be to the advantage of the NDP and the disadvantage of the UCP, whose core support is in more rural parts of Alberta.

So, the governing UCP has passed a plan to select a committee to set up a new electoral district committee, which would be stacked with UCP members and would therefore be more amenable to UCP goals (i.e. continued power). The UCP's "alternative" electoral map would have more than a dozen new merged urban and rural ridings, which would effectively dilute the power of the urban vote in Alberta elections. The motion would also establish an expedited oversight process, which could see electoral boundaries changed without any need for public hearings.

By expressly rejecting the advice of the existing redistricting committee, and setting up this alternative committee, Smith has opened herself up to allegations of gerrymandering and anti-democratic behaviour. Former Alberta Premier Rachel Notley warns that the new committee and their proposed "alternative" election map could ensure a UCP super-majority for decades to come. She is sufficiently removed from day-to-day politics to call it what is is: cheating.

Certainly, such a bare-faced and undemocratic ("Trumpian") move is unprecedented in Canadian politics. It was only a matter of time to discover whether it would be Smith or Ontario Premier Ford who first ventured down that murky road.

Are Americans just bored with Trump?

It's no secret that Americans have had enough of Trump. Democrats, obviously, never wanted or liked him, but it's now becoming clear that even many Republicans are over him. Opinion polls show him to be more unpopular than ever. Even Tucker Carlson and his brother have come out publicly to apologize to the American public and to admit that they made a mistake in supporting and glorifying Trump.

So, what gives? It's taken them long enough, but even those Trump supporters who thought they really liked his folksy-but-confrontational approach are starting to realize that folksy-but-confrontational ALL THE TIME can be exhausting. People are fed up with the constant low-level anxiety, the whiplash from repeated flip-flops, the exhaustion from dealing with his constant outrage, hissy-fits, insults, exaggerations and lies. Essentially, people are just bored with Trump. If nothing else, they are bored with his poor many decisions. (I know I am.) Clowns can be amusing for a while, but they quickly pall.

And that's not even taking into account the realization that is starting to take hold in some disillusioned voters that all those higher prices, the disrupted and limping economy, and the possibly irreparable hit to America's reputation and international standing, are actually all due to Trump's failed and misguided policies. Call it political caveat emptor. 

Perhaps, the real surprise is that 30% or so of Americans are still willing to support him, although a good proportion of his base do not seem politically sophisticated enough to piece together what seems to so obvious to everyone else.

Is the Trump administration colluding in insider trading?

Throughout Donald Trump's second term, there have been many market-moving statements and announcement, more than in any other presidential term in living memory. Whether it is to do with the war in Iran, incursions into Venezuela, or just the never-ending series of announcements about tariffs early in his tenure, few (if any) presidents have made so many, and so consequential, public announcements that have had significant effects on the stock markets and resource prices. 

Often, they were just throwaway, late-night posts on Truth Social or other social media, but many of them were enough to send the already-jittery markets into a tailspin or a mysterious upsurge. Coincidence? I think not!

There is an increasing body of evidence that suggests that there was a suspicious surge in trading activity before many of these announcements, which has some commentators posing allegations of insider trading. There are many documented examples of traders betting millions of dollars on the exchanges just hours, or even minutes, before major policy announcements. The BBC details many such examples, and The Guardian has calculated that there may have been a least a billion dollars in suspiciously "perfectly-timed" trades, as well as online betting on platforms like Polymarket and Kalshi, during the Iran war alone. Notably, Donald Trump's own net worth has nearly doubled during his second term, which is only, lest we forget, just over a year old.

Insider trading - stock trading based on non-public information about a company or sector - is hightly illegal in America, as elsewhere. Some US senators have called for a probe into possibly insider trading during the height of the tariff nonsense. 

It is, however, notoriously difficult to prove such allegations, and the laws are very difficult to enforce. There is a strong chance that no-one will ever be prosecuted. Including, of course, Trump himself, and his family and close advisors.

Should (could?) Canada join the European Union?

I confess I hadn't really noticed it, but apparently  there is talk in some circles about what a good idea it would be for Canada to join the European Union (EU).

Wait, what? That's nuts! Well, yes, it is. 

Now, to be clear, this is not a full-blown movement. It's a few off-the-cuff comments by minor (or sometimes not-so-minor) members of the Finnish, German and French governments. The only not-so-minor Canadian who seems sold on the idea is Thomas Lucaszuk, a former Alberta cabinet minister, and he's pretty minor. But a recent Nanos poll suggests that nearly 58% of Canadians would be open to the idea.

Access to the world's second-largest economic bloc might be nice. But the implications of such a union would be stark. I know we are in the throes of a bad break-up with the USA, but to then look to throw in our lot with another behemoth would be the worst kind of rebound relationship. 

This is not just Canada joining the Eurovision Song Contest. Becoming part of the EU, would mean de facto rule from Brussels - a common trade and tariffs policy (including the renegotiation of all current trade treaties), a common foreign policy, a common agricultural policy, a common fiscal policy, possibly a common currency. We would be subject to European laws and regulations, from the environment to finance to labour laws. It would amount to an almost complete loss of sovereignty, at a time when we're just realizing how valuable that is.

Luckily, it's not going to happen. Article 49 of the Treaty on European Union reserves membership to "any European state", which, last time I looked, we are most definitely not. And, anyway, we already have access to European trade through the Canada-European Union Economic and Trade Agreement (CETA) - not perfect access by any means, but still pretty good. The experience of negotiating even that agreement was fraught enough - there is no way that all 27 member states would vote to allow Canada into their club.

I'm not sure that the suggestion was all that serious, just the kind of thing politicians throw around to make a point. But we should probably be grateful for that. Make nice with Europe by all means - it is a pretty civilized and sensible organization in an increasingly dysfunctional world - but don't even consider throwing caution to the wind and joining as a full member. Even the Eurovision Song Contest is controversial enough.

Japanese PM gushes over Deep Purple

This is great. It turns out that Japan's first ever female Prime Minister, Sanae Takaichi, is a hard rock devotee and a super-fan of British band Deep Purple.

Takauchi is herself a keen (and apparently frenetic) rock drummer, and used to play in a Deep Purple tribute band. So, when she met up with DP drummer Ian Paice, over 50 years after DP's seminal 1972 album Made In Japan, Ms. Takaichi's reaction was precious: "You are my god", she gushed, not words you often hear from a Prime Minister. She added, "These days, when I fight with my husband, I drum to Burn and cast a curse on him". Er, OK, perhaps a little too much ioformation.

In the midst of trade wrangling with America, increasing tensions with China, and complaints about inflation and a sluggish economy, thoigh, what a breath of fresh air.

The achievements and costs of the US war in Iran

Trump, Hegseth & Co have been claiming overhelming victory since pretty much Day 1 of the US-Israeli war against Iran. I've lost count of the number of times both guys have claimed to have "obliterated" Iran's offensive and defensive capabilities, despite the fact that they continue, even now, bombing US allies and bases and even shooting down American aircraft.

Now Pakistan and China has come to their rescue by negotiating a two week ceasefire, giving Trump a much-needed potential way out after his wild, genocidal talk about "a whole civilization will die tonight". What little credibility Trump had is now shot, and his popularity at home has tanked even further.

So, this is perhaps not a bad juncture to stand back and assess exactly what Trump has achieved in Iran, and at what cost. Of course, the BBC has done my work for me.

America's goals on Iran have been a constantly moving target, depending who is talking, when, and the spin they want to impose. But preventing Iran for developing nuclear weapons was always near the top of the list. Thing is, Iran has hardly any nuclear weapon development anyway, and what agreements and negotiations there were have all been derailed by Trump himself and his bull-in-a-china-shop approach. Art of the deal, my ass! 

It is thought that Iran probably still has enriched uranium salted away, even after five weeks of war and the unilateral strikes in nuclear facilities last June, and most diplomats believe that it is just not possible to stop Iran's nuclear ambutions by brute force alone. And Iran remains just as defiant - perhaps even more so - about its independence and automomy as ever.

Regime change was one of the early American goals, although that aspect has been back-pedalled more  recently. Remember "keep protesting, help is on the way"? By taking out Ayatollah Ali Khomeini, all they succeeded in doing is paving the way for an equally radical and much youmger Mojtaba Khomeini. The regime, as such, remains very much in place.

Trump and Hegseth have also repeatedly.clzimed to have destroyed ("obliterated!") Iran's conventional arsenal - missiles, launchers, drones, arms factories amd navies. However, leaked intelligence assessments suggest that only about half of Iran's pre-war arsenal has actually been destroyed. Certainly, Iran seems to have continued its bombing and drone attacks on US allies and bases in the Gulf, and it has shot down at last two supposedly-unbeatable American fighter jets in his last week alone.

Meanwhile, the war has been costing the USA more than a billion dollars a day, a price most Americans are probably blissfully unaware of. All those Tomahawk missiles don't come cheap. 13 US  service member have died and hundreds more injured, which is peanuts compared to the huge Iranian casualties, buy more than many Americans, including anyi-interventionist MAGA voters, would be comfortable with for an unnecessary wat of this kind.

And the damage to the country's reputation, and Trump's own brand? Incalculable.

I don't recommend tattoos

I don't have any tattoos. I don't actually like tattoos; I don't find them cool or attractive. But they are ubiquitous these days, as much among soccer moms and college students as among gang members and criminals. And it turns out they ate not risk-free.

Setting aside the risk of infection inherent in any procedure that involves piecing the skin, which can be largely mitigated by using a reputable and licensed tattoo parlour, tattoo pigments can interact with the body's immune system in ways we are only beginning to understand.

Tattoo inks are not biologically inert - some inks can contain heavy metals like nickel, chromium, cobalt, even lead, as well as organic compounds like azo dyes and polycyclic hydrocarbons aromatic. They remain in the body for decades, interacting with the sun and breaking down into other chemicals, potentially triggering allergic reactions, immune sensitivities, genetic damage and cancers. They can also reduce the effectiveness of certain vaccines.

Tattoo ink does not stay just under the skin; it can migrate through the lymphatic system and accumulate in the lymph nodes, structures that help coordinate immune responses. There is evidence from animals studies (but, as yet, not human studies) suggesting that tattoo inks can cause carcinogenic by-products as they degrade over time or from exposure to ultraviolet light or laser removal. Cancers can take decades to develop in humans, so definitive research is difficult.

So, it's not absolutely certain that tattoos are dangerous (except for the immuno-compromised). But the odds are pretty strong. I won't be getting a tattoo any time soon, although not necessarily for that reason.